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Toxicological emergencies

One phone number covers most poison emergencies. Carbon monoxide is different — you leave first, then call. Smoke inhalation warrants medical evaluation even without symptoms. Contaminated water ingestion should never lead to inducing vomiting. This page covers all four.

Skill AreaFirst Aid and Health
TopicToxicological Emergencies
TypeInfo Page

01 — Poison Control

One number covers all poisoning questions in the United States. You do not need to be in crisis to call.

1-800-222-1222
National Poison Help Hotline. Toll-free, available 24/7, staffed by medical professionals. Routes to your regional center. Works from any phone, anywhere in the U.S.

The American Red Cross directs people to call the National Poison Help Hotline (1-800-222-1222) for any suspected poisoning where the person is alert and responsive. Poison control specialists will ask what was taken, how much, when, and the person's weight, and will advise on whether home observation is appropriate or emergency care is needed. Post this number where it is easy to find before an emergency happens.

Call 911 directly, without calling Poison Control first, if the person is unconscious, is having a seizure, is unable to breathe, or cannot be awakened. These are signs the poisoning is already severe enough to require immediate emergency response.

Outdated practice

Induce vomiting to remove a swallowed poison as quickly as possible. Keep syrup of ipecac in the medicine cabinet for this purpose.

Current guidance (Red Cross, Mayo Clinic, AAP)

Do not induce vomiting. The American Academy of Pediatrics, the American Association of Poison Control Centers, and the Red Cross no longer endorse inducing vomiting after poisoning. It provides little benefit and increases risks including aspiration of corrosive substances. Ipecac syrup should be discarded if you still have it. Always call Poison Control for specific guidance.

02 — Carbon monoxide poisoning

Get outside immediately. CO is colorless and odorless — by the time symptoms appear, the gas has already been building up.

Carbon monoxide (CO) is produced by incomplete combustion of fuel. Sources include gas furnaces, water heaters, generators, vehicle exhaust in enclosed spaces, gas stoves, and charcoal or propane grills used indoors. CO displaces oxygen in the bloodstream. Because it is colorless and odorless, poisoning can progress before anyone realizes what is happening. Multiple people in the same space becoming ill simultaneously is a classic pattern.

Carbon monoxide symptoms:

  • Headache (most common first sign)
  • Dizziness or lightheadedness
  • Weakness or fatigue
  • Nausea or vomiting
  • Confusion
  • Sleepiness
  • Chest pain
  • Loss of consciousness (severe)

The action sequence from the Red Cross is clear: if CO poisoning is suspected, get outside to fresh air immediately, and then call 911. Do not go back inside for any reason until emergency responders confirm it is safe. If the CO alarm activates, treat it as a real emergency every time, not a false alarm to investigate.

People who are unconscious in a CO-contaminated environment should be removed by emergency responders with breathing equipment, not by bystanders who may become incapacitated themselves. Call 911 and report that CO is suspected.

Seek care even after symptoms improve

Symptoms of CO poisoning can temporarily improve in fresh air and then return. Anyone with significant CO exposure should be evaluated by medical personnel, including people who feel better after leaving the building. CO causes damage that may not be fully apparent immediately.

03 — Smoke inhalation and contaminated water

Smoke inhalation warrants medical evaluation even when the person feels fine. Contaminated water ingestion requires Poison Control, not induced vomiting.

Smoke inhalation during a fire exposes the airway to particulate matter, carbon monoxide, and toxic gases from burning materials. Initial symptoms may be mild — coughing, a sore throat, or slight shortness of breath — but airway swelling and pulmonary injury can develop hours after exposure. Anyone who has been in a structure fire, been in a space with heavy smoke, or has facial burns, singed eyebrows or nasal hairs, or soot around the nose and mouth should receive medical evaluation, even if they feel well at the time.

Symptoms that indicate more serious smoke inhalation and require immediate emergency care include severe coughing, difficulty breathing, hoarseness, stridor (a high-pitched breathing sound), worsening chest pain, confusion, or loss of consciousness. Call 911 for any of these. Move the person to fresh air and loosen anything around the neck.

For suspected contaminated water ingestion, the Red Cross and Poison Control guidance is the same as for other ingested poisons: call 1-800-222-1222 for direction, do not give anything to eat or drink unless told to, and do not induce vomiting. If the water ingestion was accidental and the person is alert, Poison Control can help assess the level of risk based on the type of contamination and amount ingested. If the person develops serious symptoms after drinking contaminated water, call 911.

Quick reference

  • Poison Control: 1-800-222-1222 — call for any suspected poisoning where the person is alert; toll-free, 24/7, routes to your regional center
  • Call 911 directly (not Poison Control first) if the person is unconscious, seizing, cannot breathe, or cannot be awakened
  • Do not induce vomiting — ipecac syrup is no longer recommended; it can worsen outcomes with corrosive substances
  • CO poisoning: get outside to fresh air immediately, then call 911; do not go back inside
  • CO symptoms: headache, dizziness, weakness, nausea, confusion, sleepiness — multiple people ill at once in the same space is a key pattern
  • Smoke inhalation: get to fresh air; seek medical evaluation even without symptoms; airway swelling can develop hours later
  • Contaminated water ingestion: call Poison Control for guidance; do not induce vomiting

Primary sources

  1. Red Cross — Poison Exposure: Signs, Symptoms, and First Aid: Call 1-800-222-1222 for alert patients; call 911 if unresponsive or seizing; do not give food or drink unless advised; inducing vomiting often causes additional harm and is not recommended.
  2. Red Cross — Poisoning: CO symptoms: headache, dizziness, weakness, nausea, vomiting, sleepiness, confusion; if suspected, get outside to fresh air immediately, then call 911.
  3. Poison Control — First Aid for Poisonings: Do not induce vomiting; call 1-800-222-1222 or use webPOISONCONTROL; move inhaled poison victims to fresh air immediately.
  4. Mayo Clinic — Poisoning: First Aid: Do not give syrup of ipecac or induce vomiting; expert groups including AAP and American Association of Poison Control Centers no longer endorse ipecac; call 911 for drowsy, unconscious, or seizing patients.